Loading patent…
AssigneeBeijing Biosis Healing Biological Technology Co., Ltd.
InventorsYiqian Huang, Pengfei Wei, Wei Jing, Xueqiao Yu, Yan Zhang, Bo Zhao
Estimating the term…
In view of the shortcomings of low tissue adhesiveness or low tissue compliance and the problems of about low operability and inadequate convenience and portability of current tissue sealing materials, the present application provides an absorbable biological patch with self-adhesiveness, comprising a substrate layer and an adhesive coating located on the substrate layer, wherein the substrate layer is a biological material, and the adhesive coating is a succinimidyl ester group-grafted polyacrylic crosslinked copolymer, and optionally comprises a biodegradable polymer. The biological patch can be adhered firmly to the tissue surface and applied directly without extra preparation, and has good biocompatibility, has biodegradability, and can be used in common clinical scenarios such as tissue adherence, wound hemostasis, and low-pressure leakage of body fluids.
A self-adhesive absorbable biological patch, comprising a substrate layer and an adhesive coating located on the substrate layer, wherein the substrate layer is a biological material;
A dry adhesive material for bonding a tissue surface, comprising a succinimidyl ester group-grafted polyacrylic crosslinked copolymer, and further comprising a biodegradable polymer;
A precursor solution mixture comprising, based on a total mass of the mixture, 5.0 to 30.0 wt. % of acrylic acid and/or acrylamide, 0.2 to 5.0 wt. % of acrylated biodegradable polymer, 0.1 to 5.0 wt. % of acrylic acid-N-succinimidyl ester, 0 to 15.0 wt. % of biodegradable polymer, and a crosslinking amount of crosslinking agent.
Dependencies are inferred from the claim text.