Methods for treating ocular Demodex using spinosad formulations
AssigneeTarsus Pharmaceuticals, Inc.
InventorsBobak Robert Azamian, Douglas Michael Ackermann, Shawn D. Hickok, Joseph G. Vehige
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Abstract
Disclosed herein are methods for treating or preventing ophthalmic and dermatologic conditions in a patient, including ocular surface conditions such as blepharitis. The methods can include topically administering directly to an ocular surface of one or more eyes of a patient in need of treatment thereof an effective amount of an isoxazoline parasiticide, formamidine parasiticide, or other active ingredient, formulated into an ophthalmic composition, the ophthalmic composition further comprising a pharmaceutically acceptable vehicle. Compositions are also disclosed.
Claims19
A method for treating an ocular Demodex mite infestation, comprising topically administering to one or more of the eye, eyelid, or eyelashes of a human patient in need of treatment thereof an effective amount of a composition comprising spinosad and an isoxazoline parasiticide.
A method for treating meibomian gland dysfunction caused by an ocular Demodex mite infestation, comprising topically administering to one or more of the eyelid or eyelashes of a human patient in need of treatment thereof an effective amount of a composition comprising spinosad and an isoxazoline parasiticide.
A method for treating Demodex blepharitis, comprising topically administering to one or more of the eyelid or eyelashes of a human patient in need of treatment thereof an effective amount of a composition comprising spinosad and an isoxazoline parasiticide.
Dependencies are inferred from the claim text.