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US 12,661,331 B2Granted
MEK inhibitors for the treatment of hantavirus infections
AssigneeAtriva Therapeutics GmbH
InventorOliver Planz
Life of this patent
Estimating the term…
Abstract
The present invention relates to MEK inhibitors that are capable of displaying one or more beneficial therapeutic effects. The MEK inhibitors can be used in the prevention and/or treatment of hantavirus infection.
Claims14
A method of preventing or treating of a hantavirus infection in a mammal comprising:
- identifying the mammal as in need of prophylaxis on the basis of exposure to hantavirus infection or as in need of treatment on the basis of evidence of an acute hantavirus infection,
- administering to the mammal in need thereof a therapeutically effective amount of a MEK inhibitor, wherein the MEK inhibitor is CI-1040 or PD-0184264, or pharmaceutically acceptable salt or metabolite thereof.
A method of preventing a hantavirus infection in a mammal comprising:
- identifying the mammal as in need of prophylaxis on the basis of having an exposure to rodents or rodent excrement within a period of between 12 hours and 10 days prior to the administration,
- administering to the mammal in need thereof a therapeutically effective amount of a MEK inhibitor, wherein the MEK inhibitor is CI-1040 or PD-0184264, or pharmaceutically acceptable salt or metabolite thereof.
Dependencies are inferred from the claim text.