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US 12,661,327 B2Granted
Aqueous patch
AssigneeTeikoku Seiyaku Co., Ltd.
InventorMasahiro Inazuki
Life of this patent
Estimating the term…
Abstract
The purpose of the present invention is to provide an aqueous patch in which basic physical properties as an aqueous patch are less likely to deteriorate and crystals of 1-menthol are less likely to precipitate. The aqueous patch includes, in a pasty preparation, 1-menthol: 0.5% by mass or more and 10% by mass or less, an oil component: 0.2% by mass or more and 19% by mass or less; and silica: 0.1% by mass or more and 5.5% by mass or less.
Claims6
An aqueous patch comprising, in a pasty preparation,
- 1-menthol:
- 0.5% by mass or more and 10% by mass or less,
- an oil component:
- 0.2% by mass or more and 19% by mass or less;
- silica:
- 0.1% by mass or more and 5.5% by mass or less;
- a drug;
- a water-soluble polymer material;
- and
- water,
- wherein the drug comprises at least one selected from the group consisting of lidocaine and a pharmaceutically acceptable salt thereof,
- wherein the oil component comprises castor oil,
- wherein the ratio of total mass of the drug and the 1-menthol to mass of the oil component is 0.3 or more and 12 or less,
- wherein the pasty preparation does not comprise loxoprofen or a pharmaceutically acceptable salt thereof, wherein the pasty preparation does not comprise methyl salicylate, and
- wherein the pasty preparation does not comprise polybutene.
12 more elements
Dependencies are inferred from the claim text.