Body lumen wall invagination

A tissue grasper comprising:

• an elongated tubular body having a proximal end and a distal end, wherein said proximal end is connected to a vacuum source;
• a collapsible distal suction cup coupled to said distal end, defining a distal opening and an internal lumen, wherein said collapsible distal suction cup is configured to apply vacuum from said vacuum source through said distal opening on a LAA wall with a force sufficient to convex a portion of said LAA wall into said lumen, and to controllably collapse on said convexed portion of the LAA with a force sufficient to hold said convexed portion in said lumen;
• wherein said collapsible distal cup comprises a plurality of spaced-apart extensions movably coupled to said elongated tubular body and arranged on a circumference of the elongated tubular body distal end, wherein in an open expanded state of said collapsible distal cup said plurality of spaced-apart extensions are tilted outwardly, and wherein in a collapsed state of said collapsible distal cup, said plurality of spaced-apart extensions move inwardly and press against said convexed portion of said LAA with a force sufficient to hold said convexed LAA portion in said lumen;
• wherein at least some of said plurality of spaced-apart extensions are interconnected by at least one wire, wherein application of force on said wire controllably move said collapsible distal cup between said open expanded state and said collapsed state, by moving said at least some of said plurality of spaced-apart extensions.