Hazard based assessment patterns
AssigneeRoche Diabetes Care, Inc.
InventorsAbhishek Soni, David L. Duke
Life of this patent
Estimating the term…
Abstract
Methods and devices for retrospectively assessing continuous monitoring reference pattern data to determine a risk of a patient glucose level measurement taken in at least one data segment being outside a predetermined range. The methods and devices can include executing an algorithm to compare risk scores derived from reference pattern data in a currently collected data segment with risk scores of previously stored reference pattern data of previously collected data segments for a patient for assessing risk.
Claims20
A computer implemented display method for displaying a reference pattern plot of analyte concentrations and related reduced rank vectors of matching risk patterns in a reduce rank space and for performing user-controlled interactions to select one of the matching risk patterns, comprising:
- processing with a processor data which comprises a plurality of analyte level measurements acquired from a physiological data input device to generate a reference pattern plot of analyte concentrations over time from the data, the reference pattern plot comprising a reference risk pattern, the reference risk pattern comprising both increasing and decreasing analyte concentration values over a period of time and an assigned risk score;
- retrieving previously determined risk patterns and corresponding previously assigned risk scores from memory by the processor;
- determining by the processor matching ones of the previously determined risk patterns to the reference risk pattern of the reference pattern plot of analyte concentrations over time such that non-matching ones of the previously determined risk patterns are excluded for further processing and display;
- displaying by the processor via a Graphical User Interface (GUI) the reference risk pattern of the reference pattern plot of analyte concentrations over time;
- displaying by the processor via the GUI the matching ones of the previously determined risk patterns as related matching reduced rank vectors;
- displaying by the processor via the GUI raw data for the matching reduced rank vectors, wherein the matching reduced rank vectors are displayed via the GUI as smooth lines, and the raw data for the matching reduced rank vectors are displayed via the GUI as noisy lines;
- scrolling through the displayed matching reduced rank vectors via the GUI to select a specific matching risk pattern from the previously determined risk patterns to the displayed reference risk pattern on the reference pattern plot from the displayed matching reduced rank vectors;
- comparing the assigned risk score of the reference risk pattern to a selected previously assigned risk score, which is the previously assigned risk score of the specific matching risk pattern as selected, to generate a risk score comparison difference value;
- sending an alert to display when the risk score comparison difference value, generated from a difference between the assigned risk score compared to the selected previously assigned risk score, is outside a predetermined risk score comparison range, the predetermined risk score comparison range comprising a lower range value and an upper range value, such that the risk score comparison difference value based on the difference between the assigned risk score and the selected previously assigned risk score is less than the lower range value or greater than the upper range value of the predetermined risk score comparison range to thus be outside of the predetermined risk score comparison range;
- and
- automatically adjusting therapy, by a computing device communicatively coupled to the processor, including automated delivery operatively by the computing device of an adjusted insulin bolus to implement a target return path from a detected glucose state to arrive at a target glucose state and treat diabetes based on the alert when the risk score comparison difference value is outside the predetermined risk score comparison range.
A system for displaying a reference pattern plot of analyte concentrations and related reduced rank vectors of matching risk patterns in a reduce rank space and for performing user-controlled interactions to select one of the matching risk patterns, comprising:
- a physiological data input device;
- a display;
- a memory;
- and
- a processor operably connected to the physiological data input device, the display and memory, wherein the processor is programmed to:
- process data which comprises a plurality of analyte level measurements acquired from the physiological data input device to generate a reference pattern plot of analyte concentrations over time from the data, the reference pattern plot comprising a reference risk pattern, the reference risk pattern comprising both increasing and decreasing analyte concentration values over a period of time and an assigned risk score,
- retrieve previously determined risk patterns and corresponding previously assigned risk scores from the memory,
- determine matching ones of the previously determined risk patterns to the reference risk pattern of the reference pattern plot of analyte concentrations over time such that non-matching ones of the previously determined risk patterns are excluded for further processing and display,
- display a Graphical User Interface (GUI) on the display that shows the reference risk pattern of the reference pattern plot of analyte concentrations over time,
- display via the GUI the matching ones of the previously determined risk patterns as related matching reduced rank vectors,
- display via the GUI raw data for the matching reduced rank vectors, wherein the matching reduced rank vectors are displayed on the GUI as smooth lines, and the raw data for the matching reduced rank vectors are displayed on the GUI as noisy lines,
- scroll via the GUI the displayed matching reduced rank vectors upon user interaction to select a specific matching risk pattern from the previously determined risk patterns to the displayed reference risk pattern on the reference pattern plot from the displayed matching reduced rank vectors;
- compare the assigned risk score of the reference risk pattern to a selected previously assigned risk score, which is the previously assigned risk score of the specific matching risk pattern as selected, to generate a risk score comparison difference value;
- send an alert to display when the risk score comparison difference value, generated from a difference between the assigned risk score compared to the selected previously assigned risk score, is outside a predetermined risk score comparison range, the predetermined risk score comparison range comprising a lower range value and an upper range value, such that the risk score comparison difference value based on the difference between the assigned risk score and the selected previously assigned risk score is less than the lower range value or greater than the upper range value of the predetermined risk score comparison range to thus be outside of the predetermined risk score comparison range;
- and
- automatically adjust therapy, by a computing device communicatively coupled to the processor, including automated delivery operatively by the computing device of an adjusted insulin bolus to implement a target return path from a detected glucose state to arrive at a target glucose state and treat diabetes based on the alert when the risk score comparison difference value is outside the predetermined risk score comparison range.
Dependencies are inferred from the claim text.