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US 12,656,293 B2Granted
Diffusion control layer for use in electrochemical sensors
AssigneeMedtronic, Inc.
InventorsJennifer Lorenz Marckmann, Mohsen Askarinya, David L. Probst, John E. Burnes
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Abstract
An electrochemical sensor may include a common reference electrode, at least one counter electrode, and a work electrode platform including a work electrode and at least one diffusion control layer. The work electrode may be electrically coupled to the common reference electrode. The electrode may include a reagent substrate configured to react with an analyte to produce a signal indicative of a concentration of the analyte. The at least one diffusion control layer may be configured to control the diffusion of the analyte to the work electrode.
Claims15
An electrochemical sensor comprising:
- a common reference electrode;
- at least one counter electrode;
- and
- a work electrode platform comprising a first work electrode disposed on a first portion of a surface, a second work electrode laterally neighboring and in contact with the first work electrode and disposed on a second portion of the surface contiguous to the first portion of the surface, and at least one diffusion control layer coextensive to a pair of opposed ends of the first work electrode and the second work electrode, the at least one diffusion control layer comprising a matrix material defining a plurality of pores,
- wherein the second work electrode is electrically coupled to the common reference electrode,
- wherein the first work electrode comprises a first reagent substrate configured to react with a first analyte to produce a first signal indicative of a concentration of the first analyte,
- wherein the second work electrode comprises a second reagent substrate configured to react with a second analyte to produce a second signal indicative of a concentration of the second analyte,
- wherein the at least one diffusion control layer is configured to control diffusion of the first analyte through the plurality of pores of the at least one diffusion control layer to the first work electrode and diffusion of the second analyte through the plurality of pores of the at least one diffusion control layer to the second work electrode, and
- wherein the at least one diffusion control layer comprises at least two dissolvable diffusion control layers being laterally adjacent to each other, the at least two dissolvable diffusion control layers comprising a first dissolvable diffusion control layer covering a surface of the first reagent substrate and a second dissolvable diffusion control layer covering a surface of the second reagent substrate.
6 more elements
A method of forming an electrochemical sensor, the method comprising:
- forming a common reference electrode;
- forming at least one counter electrode;
- and
- forming a work electrode platform comprising a first work electrode disposed on a first portion of a surface, a second work electrode laterally neighboring and in contact with the first work electrode and disposed on a second portion of the surface contiguous to the first portion of the surface, and at least one diffusion control layer coextensive to a pair of opposing ends of the first work electrode and the second work electrode, the at least one diffusion control layer comprising a matrix material defining a plurality of pores,
- wherein the second work electrode is electrically coupled to the common reference electrode,
- wherein the first work electrode comprises a first reagent substrate configured to react with a first analyte to produce a signal indicative of a concentration of the first analyte,
- wherein the second work electrode comprises a second reagent substrate configured to react with a second analyte to produce a signal indicative of a concentration of the second analyte,
- wherein the at least one diffusion control layer is configured to control diffusion of the first analyte through the plurality of pores of the at least one diffusion control layer to the first work electrode and diffusion of the second analyte through the plurality of pores of the at least one diffusion control layer to the second work electrode, and
- wherein the at least one diffusion control layer comprises at least two dissolvable diffusion control layers being laterally adjacent to each other, the at least two dissolvable diffusion control layers comprising a first dissolvable diffusion control layer covering a surface of the first reagent substrate and a second dissolvable diffusion control layer covering a surface of the second reagent substrate.
6 more elements
Dependencies are inferred from the claim text.