Cell or tissue embedding device
AssigneesJapan Vam & Poval Co., Ltd., National University Corporation Tohoku University
InventorsAkinobu Oharuda, Yoshihiro Kimura, Masafumi Goto
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Abstract
A cell or tissue embedding device highly capable of supplying a physiologically active substance is disclosed. The device includes an aqueous gel that serves as an immunoisolation layer and the aqueous gel includes a polyvinyl alcohol resin with a syndiotacticity of 32 to 40% in triad. A process of preparing a PVA gel containing living cells or living tissue is disclosed and the process provides less reduction of the living cells or living tissue during preparation of the PVA gel.
Claims13
A cell or tissue embedding device having an aqueous gel serving as an immunoisolation layer, the aqueous gel comprising a polyvinyl alcohol resin having a syndiotacticity of 32 to 40% in triad, wherein pancreatic islets are embedded in the immunoisolation layer,
- wherein the aqueous gel has a gelation at a temperature of −5° C. or higher, and
- wherein the polyvinyl alcohol resin has a polymerization degree of 1000 to 5000.
A cell or living tissue embedding device having an aqueous gel serving as an immunoisolation layer, the aqueous gel comprising a polyvinyl alcohol resin having a syndiotacticity of 32 to 40% in triad and pancreatic islets, which allows penetration of a component secreted by the pancreatic islets embedded therein while inhibiting penetration of immune-related cells or an immune-related substance,
- wherein the aqueous gel has a gelation at a temperature of −5° C. or higher, and
- wherein the polyvinyl alcohol resin has a polymerization degree of 1000 to 5000.
Dependencies are inferred from the claim text.