Loading patent…
AssigneeCytiva Sweden AB
InventorsTuomo Frigård, Camilla Estmer Nilsson, Patricia Roch, Björn Markus Olovsson, Magnus Wetterhall, Nils Stafström, Inger Salomonsson
Estimating the term…
The present invention relates to a computer implemented method for controlling a fluid coupling network (170), the fluid coupling network (170) being configured to be fluidly couplable to bioreactor (110), a gas source (120), a buffer source (140), a waste port (150), a processing system (160) and a conduit reservoir (208), the fluid coupling network (170) comprising a barrier unit (220) configured to sterilely separate fluid paths within the fluid coupling network (170), the fluid coupling network (170) being controllable to sample the bioreactor (110), the method comprising obtaining (510) a fluid sample from the bioreactor (110), wherein the step of obtaining the fluid sample comprises controlling a flow of fluid from the bioreactor (110) via the conduit reservoir (208) and the fluid coupling network (170) to the waste port (150), to fill the conduit reservoir (208) with the fluid from the bioreactor (110), providing (530) the fluid sample, wherein the step of providing the fluid sample comprises to provide the fluid sample to the processing system (160) from the conduit reservoir (208) via the fluid coupling network (170), and returning (540) residual fluid sample to the bioreactor (110), wherein the residual fluid sample is comprised by a part of the fluid coupling network (170) separated by the barrier unit (220), wherein the step of returning residual fluid sample comprises controlling a flow of gas from a gas source (120) to the bioreactor (110) via the part of the fluid coupling network (170).
A computer implemented method for controlling a fluid coupling network, the fluid coupling network being configured to be fluidly couplable to bioreactor, a gas source, a buffer source, a waste port, a processing system and a conduit reservoir, the fluid coupling network comprising a barrier unit configured to sterilely separate fluid paths within the fluid coupling network, the fluid coupling network being controllable to sample the bioreactor, the method comprising:
A barrier unit configured to sterilely separate fluid paths within a fluid coupling network, the fluid coupling network being configured to be fluidly couplable to a bioreactor and a gas source, wherein the barrier unit sterilely separates fluid paths of part of the fluid coupling network from fluid paths of a remaining part of the fluid coupling network, wherein the barrier unit, operating in a first operational state, allows fluid to flow from the part of the fluid coupling network to remaining part of the fluid coupling network and the barrier unit, operating in a second operational state, prevents fluid to flow from the part of the fluid coupling network to the remaining part of the fluid coupling network, and wherein the barrier unit is configured to sterilely separate the part of the fluid coupling network, the part comprising the fluid paths that fluidly couple the bioreactor and the gas source.
A fluid coupling network, the fluid coupling network being configured to be fluidly couplable to bioreactor, a gas source, a buffer source, a waste port a processing system and a conduit reservoir, the fluid coupling network comprising a barrier unit configured to sterilely separate fluid paths within the fluid coupling network, the fluid coupling network being controllable to sample the bioreactor, wherein the fluid coupling network is configured to:
Dependencies are inferred from the claim text.