Cell culture chamber device for cell and tissue growth

A cell culture chamber device for the growing of cell cultures and tissues, the cell culture chamber device comprising

• an enclosure configured to contain a cell culture media, and
• a first end, a second end, and at least one connecting wall connecting the first and the second ends, where the first end, the second end, and the at least one connecting wall at least in part defines the enclosure, wherein the first end, or a part or window thereof, is substantially transparent and the second end and/or at least one of the at least one connecting wall, or a respective part or window thereof, is/are substantially transparent or is/are substantially translucent, where the first end or the part or window thereof is configured to be optically or otherwise aligned, at least for some period of time or periodically, with the second end or the part or window thereof and/or with the at least one of the at least one connecting wall or the part or window thereof so that light or another illumination or visualisation signal, transmitted through or by the second end or the part or window thereof and/or through or by the at least one of the at least one connecting wall or the part or window thereof into the enclosure, is transmitted or propagates through at least a part of the cell culture media and out through the first end or the part or window thereof to outside the cell culture chamber device, and
• wherein the cell culture chamber device is configured to rotate about a predetermined rotational axis, and wherein the cell culture chamber device further comprises a circumferential gas exchanger
• arranged circumferentially about or along at least a part of the enclosure or about a central and/or lengthwise axis of the cell culture chamber device, or about a predetermined rotational axis, and
• comprising a cavity comprising a volume connecting a gas exchange interface of the enclosure with ambient air or gas of the cell culture chamber device.

A cell culture chamber device for the growing of cell cultures and tissues, the cell culture chamber device comprising

• an enclosure configured to contain a cell culture media, and
• a first end, a second end, and at least one connecting wall connecting the first and the second ends, where the first end, the second end, and the at least one connecting wall at least in part defines the enclosure,
• wherein the first end, or a part or window thereof, is substantially transparent and the second end and/or at least one of the at least one connecting wall, or a respective part or window thereof, is/are substantially transparent or is/are substantially translucent,
• where the first end or the part or window thereof is configured to be optically or otherwise aligned, at least for some period of time or periodically, with the second end or the part or window thereof and/or with the at least one of the at least one connecting wall or the part or window thereof so that light or another illumination or visualisation signal, transmitted through or by the second end or the part or window thereof and/or through or by the at least one of the at least one connecting wall or the part or window thereof into the enclosure, is transmitted or propagates through at least a part of the cell culture media and out through the first end or the part or window thereof to outside the cell culture chamber device, and
• wherein the cell culture chamber device is configured to rotate about a predetermined rotational axis, wherein the second end or the part or window thereof is substantially transparent and wherein the cell culture chamber device further comprises or is connected to a light diffusor configured to receive light and to provide substantially uniform light to the second end or the part or window thereof thereby providing substantially uniform illumination of the cell culture media when contained in the enclosure, and/or wherein a respective cross section, substantially perpendicular to a central axis extending between the first and the second end, of the first end and/or the second end is/are substantially circular.

A cell culture chamber device for the growing of cell cultures and tissues, the cell culture chamber device comprising

• an enclosure configured to contain a cell culture media, and
• a first end, a second end, and at least one connecting wall connecting the first and the second ends, where the first end, the second end, and the at least one connecting wall at least in part defines the enclosure,
• wherein the first end, or a part or window thereof, is substantially transparent and the second end and/or at least one of the at least one connecting wall, or a respective part or window thereof, is/are substantially transparent or is/are substantially translucent,
• where the first end or the part or window thereof is configured to be optically or otherwise aligned, at least for some period of time or periodically, with the second end or the part or window thereof and/or with the at least one of the at least one connecting wall or the part or window thereof so that light or another illumination or visualisation signal, transmitted through or by the second end or the part or window thereof and/or through or by the at least one of the at least one connecting wall or the part or window thereof into the enclosure, is transmitted or propagates through at least a part of the cell culture media and out through the first end or the part or window thereof to outside the cell culture chamber device, and
• wherein the cell culture chamber device is configured to rotate about a predetermined rotational axis,
• wherein the first end or the part or window thereof and the second end or the part or window thereof are opposite each other in a predetermined direction along a lengthwise central axis of the enclosure and/or the cell culture chamber device where the central axis extends between the first end or the part or window thereof and the second end or the part or window thereof and the lengthwise central axis is the predetermined rotational axis.

A cell culture chamber device for the growing of cell cultures and tissues, the cell culture chamber device comprising

• an enclosure configured to contain a cell culture media, and
• a first end, a second end, and at least one connecting wall connecting the first and the second ends, where the first end, the second end, and the at least one connecting wall at least in part defines the enclosure,
• wherein the first end, or a part or window thereof, is substantially transparent and the second end and/or at least one of the at least one connecting wall, or a respective part or window thereof, is/are substantially transparent or is/are substantially translucent,
• where the first end or the part or window thereof is configured to be optically or otherwise aligned, at least for some period of time or periodically, with the second end or the part or window thereof and/or with the at least one of the at least one connecting wall or the part or window thereof so that light or another illumination or visualisation signal, transmitted through or by the second end or the part or window thereof and/or through or by the at least one of the at least one connecting wall or the part or window thereof into the enclosure, is transmitted or propagates through at least a part of the cell culture media and out through the first end or the part or window thereof to outside the cell culture chamber device, and
• wherein the cell culture chamber device is configured to rotate about a predetermined rotational axis,
• wherein the cell culture chamber device and the enclosure are configured for clinostat rotation or for rotation negating or supplementing, at least to a certain extent, the effects of gravitational pull on content in the enclosure.