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US 12,655,199 B2Granted
Tumor therapeutic agent and use thereof
AssigneeKeymed Biosciences Co., Ltd.
InventorsGang Xu, Bo Chen, Ying Wang
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Abstract
Provided is an antibody that recognizes a tight junction protein 18.2, a preparation method therefor, and a use thereof.
Claims20
An antibody or antigen-binding portion thereof that binds to human Claudin 18.2, comprising:
- a heavy chain CDR1 of SEQ ID NO:
- 207 or 232,
- a heavy chain CDR2 of SEQ ID NO:
- 208, 223, 228 or 233,
- a heavy chain CDR3 of SEQ ID NO:
- 234;
- a light chain CDR1 of SEQ ID NO:
- 262 or 267,
- a light chain CDR2 of SEQ ID NO:
- 263, and
- a light chain CDR3 of SEQ ID NO:
- 264 or 269.
9 more elements
Dependencies are inferred from the claim text.