Back to results
US 12,655,173 B2Granted
Hybrid amide derivatives of amphotericin B
AssigneeThe Board of Trustees of the University of Illinois
InventorsMartin D. Burke, Arun Maji
Life of this patent
Estimating the term…
Abstract
Disclosed are C16 amide derivatives of C2′-epi-amphotericin B (C2′epiAmB) and salts thereof, characterized by improved clinical efficacy with reduced toxicity compared to AmB. Also disclosed are pharmaceutical compositions, comprising any of the disclosed compounds or salts thereof, as well as methods of treatment and therapeutic uses of the same.
Claims13
A compound selected from the group consisting of:
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.