Small molecules with antibacterial activity

A compound of formula:

• wherein:
• one is a single bond and the other is a double bond;
• X is NH or N(RN);
• RN is alkyl, acyl, or alkoxycarbonyl, any of which is substituted or unsubstituted;
• Z is CH, C(alkyl that is substituted or unsubstituted), C(aryl that is substituted or unsubstituted), C(heteroaryl that is substituted or unsubstituted), or N;
• Y is C, wherein the connecting Y and Z is the double bond;
• L is —CH═N—NH—;
• Q1 is CH;
• Q2 is CH;
• R1 is OH, OR1a, OC(O)NH2, OC(O)NHR1a, or OC(O)N(R1a)2;
• each R1a is independently C(O)R1b, alkyl, alkenyl, alkynyl, aryl, cycloalkyl, heterocyclyl, heteroaryl, or an amino acid residue, any of which is substituted or unsubstituted;
• R1b is alkyl, alkenyl, alkynyl, aryl, cycloalkyl, heterocyclyl, or heteroaryl, any of which is substituted or unsubstituted;
• R3 is H;
• R5 is aryl, cycloalkyl, heterocyclyl, heteroaryl, or C(O)R6, wherein the aryl, cycloalkyl, heterocyclyl, or heteroaryl is substituted with halo, halo-alkyl, amino, cyano, or carboxyl;
• and
• R6 is alkyl, alkenyl, alkynyl, aryl, cycloalkyl, heterocyclyl, or heteroaryl, any of which is substituted or unsubstituted,
• or a pharmaceutically-acceptable salt thereof.