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US 12,655,089 B2Granted
Hydroxynorketamine analogues, compositions comprising same and methods of use thereof
AssigneeSpirify Pharma Inc.
InventorIrving William Wainer
Life of this patent
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Abstract
The present disclosure pertains to amino cyclohexanone compounds, pharmaceutical compositions containing same and methods of treating depression, pain, inflammation, and other clinical indications.
Claims3
An amino cyclohexanone compound of Formula (I), a stereoisomer, or a pharmaceutically acceptable salt thereof
- R1 is —H, —OH, —N3, —SR4, —SO2R4, —NHR4, or —N(R4R5);
- R2 is —H, —CN, —N3, —SR4, —SO2R4, —NHR4, or —N(R4R5);
- wherein R4 and R5 are independently selected from C1-C8 saturated or unsaturated alkyl;
- when R1 is —OH, R2 is —H, and R3 is
- when R1 is —N3, —SR4, —SO2R4, —NHR4, or —N(R4R5), R2 is —H, and R3 is
- when R1 is —H, R2 is —CN, —N3, —SR4, —SO2R4, —NHR4, or —N(R4R5);
- and
- R3 is
5 more elements
Dependencies are inferred from the claim text.