Chemical distillation system with in situ analytics

A distillation system comprising:

• a feedstock supply comprising a feedstock liquid including a volatile compound;
• an evaporator in fluid communication with the feedstock supply, the evaporator comprising a sample port and configured to vaporize the volatile compound;
• a condenser in fluid communication with the evaporator, the condenser configured to condense the vaporized volatile compound into a distillate;
• a vacuum pump configured to reduce a pressure within the evaporator to less than 750 torr;
• a sampling device in fluid communication with the sample port of the evaporator and configured to withdraw a sample of the vaporized volatile compound, the sampling device comprising a gas analyzer configured to measure a property of the sample;
• and
• a controller in communication with the gas analyzer and configured to analyze the property of the sample and adjust a parameter of the system in response to the analysis of the property:
• wherein the sampling device further comprises:
• a sample loop comprising an outlet in fluid communication with the gas analyzer and an inlet in fluid communication with the sample port of the evaporator;
• a second vacuum pump in fluid communication with the sample loop via a vacuum valve and configured to produce a pressure within the sample loop that is equal to or less than the pressure within the evaporator;
• a carrier gas port configured to introduce a carrier gas into the sample loop;
• an internal standard port configured to introduce an internal standard gas into the sample loop;
• and
• a plurality of valves;
• and
• wherein the sampling device is configured to operate in a collection mode wherein, via the plurality of the valves, the second vacuum pump, the inlet of the sample loop, and the internal standard port are isolated from the outlet and the carrier gas port is not isolated from the outlet.