Alveolar bone augmentation scaffold system
AssigneeNovaprint Therapeutics Suzhou Co., Ltd
InventorsDongxu Ke, Xi Yang
Life of this patent
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Abstract
Provided is an alveolar bone augmentation scaffold system. The scaffold system includes the following structures: a porous augmentation scaffold fabricated by 3D printing using composite materials for filling alveolar bone defects; a mechanical separating plate, wrapped around the porous augmentation scaffold with a biomimetic structure for restoring alveolar bone defects; the augmentation scaffold is provided with a first region close to dental pulp, a second region away from the dental pulp, and a third region surrounding the second region, wherein pore diameters of three-dimensional porous structure of the above three regions are R1, R2, and R3 respectively, and they satisfy R1≥R2>R3.
Claims19
An alveolar bone augmentation scaffold system, wherein the scaffold system comprises following structures:
- a porous augmentation scaffold fabricated by 3D printing using composite materials for filling alveolar bone defects;
- and
- a mechanical separating plate, wrapped around the porous augmentation scaffold with a biomimetic structure for restoring alveolar bone defects,
- wherein
- the augmentation scaffold has a first region configured to be close to dental pulp, a second region configured to be away from the dental pulp, and a third region surrounding the second region, wherein pore diameters of the three-dimensional porous structure of the above three regions are R1, R2, and R3, respectively, and they satisfy R1>R2>R3,
- wherein a polymer material of the first region is PCL-PLGA-TCP, a polymer material of the second region is PCL-TCP, and a polymer material of the third region is PCL, wherein a number-average molecular weight of the PCL in the first region and/or the second region is 1×104 Da-5×104 Da, and a number-average molecular weight of the PCL in the third region is 5×104 Da-10×104 Da.
An alveolar bone augmentation scaffold system, wherein the scaffold system comprises following structures:
- a porous augmentation scaffold fabricated by 3D printing using composite materials for filling alveolar bone defects;
- and
- a mechanical separating plate, wrapped around the porous augmentation scaffold with a biomimetic structure for restoring alveolar bone defects,
- wherein
- the augmentation scaffold has a first region configured to be close to dental pulp, a second region configured to be away from the dental pulp, and a third region surrounding the second region, wherein pore diameters of the three-dimensional porous structure of the above three regions are R1, R2, and R3, respectively, and they satisfy R1>R2>R3,
- wherein a polymer material of the first region is PCL-PLGA-TCP, polymer materials of the second and third regions are PCL-TCP, wherein a number-average molecular weight of the PCL in the first region and/or the second region is 1×104 Da-5×104 Da, and a number-average molecular weight of the PCL in the third region is 5×104 Da-10×104 Da.
Dependencies are inferred from the claim text.