Click outer membrane vesicles
AssigneeIntravacc B.V.
InventorsPeter André van der Ley, Afshin Zariri, Coen Peter Phielix, Cornelia Pia Kruiswijk
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Abstract
The specification pertains to a complex of an outer membrane vesicle (OMV), a vertebrate antimicrobial peptide (AMP) and an antigen, wherein the AMP is non-covalently complexed with the OMV and wherein the antigen is conjugated to the AMP. Preferably, the antigen is covalently linked to the AMP. The specification further concerns the induction of an immune response using the complex of the invention as well as a method for producing the complex of the invention.
Claims19
A complex of an Outer Membrane Vesicle (OMV), a vertebrate antimicrobial peptide (AMP) and an antigen, wherein the AMP is non-covalently complexed with the OMV and wherein the antigen is conjugated to the AMP, and wherein the AMP is a cathelicidin.
Dependencies are inferred from the claim text.