Nasal spray composition
AssigneeGlenmark Specialty S.A.
InventorsUlhas Dhuppad, Ashok Katkurwar, Rajesh Ankam, Pravinkumar Sharma
Life of this patent
Estimating the term…
Abstract
The present invention relates to a pharmaceutical composition in the form of an aqueous suspension suitable for nasal administration. The composition comprises mometasone furoate or a hydrate thereof, olopatadine or a pharmaceutically acceptable salt thereof (e.g., olopatadine hydrochloride), and a means for controlling clogging of an actuator and/or dip tube in a spray apparatus from which the composition is administered. The composition is suitable to provide consistent delivery, for example, for at least 5 days without clogging in the actuator or dip tube of a nasal spray device. The present invention also relates to a process of preparing the composition in the form of an aqueous suspension.
Claims14
A nasal spray device comprising a container and a dispenser head, wherein
- the dispenser head comprises a pump, a dip tube, an actuator, and a dispensing orifice,
- the container includes a pharmaceutical composition, wherein (a) the composition is in the form of an aqueous suspension suitable for nasal administration, and (b) the composition comprises mometasone furoate in an amount of about 0.025% w/w in particulate form, olopatadine hydrochloride in an amount of about 0.665% w/w in dissolved form, and about 0.05% w/w to about 0.5% w/w of a de-clogging agent, wherein the de-clogging agent is glycerin.
Dependencies are inferred from the claim text.