Benzimidazolone-based cinnamamide derivative as TRPV1 antagonist and pharmaceutical composition for treatment or prevention of pain containing same as active ingredient

A compound represented by formula 1 below, a stereoisomer thereof, a solvate thereof, a hydrate thereof or a pharmaceutically acceptable salt thereof:

• wherein:
• X1 and X2 together form a pi bond;
• and
• is unsubstituted or substituted 5-6 membered heteroaryl containing at least one heteroatom selected from the group consisting of N, O and S, or unsubstituted or substituted phenyl,
• wherein the substituted 5-6 membered heteroaryl and the substituted phenyl are independently substituted with at least one substituent selected from the group consisting of:
• C1-7 straight or branched alkyl unsubstituted or substituted with at least one halogen or hydroxy group;
• C2-7 straight or branched alkynyl;
• C3-6 cycloalkyl unsubstituted or substituted with at least one C1-5 straight or branched alkyl;
• 5-6 membered heterocycloalkyl containing at least one heteroatom selected from the group consisting of N and O unsubstituted or substituted with at least one C1-5 straight or branched alkyl;
• —NR1R2;
• —OR3;
• —SR4;
• C6 aryl unsubstituted or substituted with at least one halogen or C1-5 straight or branched alkyl;
• and 5 membered heteroaryl containing at least one heteroatom selected from the group consisting of N, O and S,
• R1 and R2 are independently C1-5 straight or branched alkyl,
• R3 is C1-7 straight or branched alkyl unsubstituted or substituted with at least one halogen, C3-6 cycloalkyl, or C1-5 straight or branched alkyl substituted with C3-6 cycloalkyl unsubstituted or substituted with at least one methyl,
• R4 is C1-7 straight or branched alkyl unsubstituted or substituted with at least one halogen, C3-4 cycloalkyl, or C1-5 straight or branched alkyl substituted with C3-6 cycloalkyl unsubstituted or substituted with at least one methyl.