Methods and apparatus for coating bone particles using a mesh
AssigneeWarsaw Orthopedic, Inc.
InventorsLeenaporn Jongpaiboonkit, William J. Bastan, Timothy Edward Holleran, Javad A. Mirza
Life of this patent
Estimating the term…
Abstract
Methods and apparatus for coating bone particles are provided. The methods and apparatus comprise providing a first mesh having a first set of openings to allow coating liquid and bone particles of a select size therethrough and bone particles larger than the select size to remain on the first mesh, the first mesh having a bottom portion; adding bone particles to the first mesh; and contacting the bone particles with coating liquid so as to allow bone particles larger than the first set of openings to remain on the first mesh so as to coat the bone particles.
Claims14
A plurality of coated porous ceramic granules comprising:
- porous ceramic granules comprising hydroxyapatite in an amount of about 8 to about 22 wt. % and beta-tricalcium phosphate in an amount of about 78 to about 92 wt. %, the porous ceramic granules having micropores having an average diameter of about 50 to about 800 μm, and the porous ceramic granules having an average particle size of about 0.1 to 2.0 mm;
- a mineral coating on each of the porous ceramic granules, the mineral coating being about 97 wt. % hydroxyapatite and about 3 wt. % octacalcium phosphate, comprising plate-like nano-apatite structures having an average size range from about 100 to about 200 nm, and having a porosity between about 20 and about 28 wt. %;
- wherein the coated porous ceramic granule has a BET surface area from about 5 to about 10 m2/g,
- wherein the mineral coating has a thickness from about 1 to about 200 nm, and is uniformly formed on the entire surface of each porous ceramic granule such that the coated porous ceramic granules have a larger BET surface area that is from about 1106% to about 1840% of that of the porous ceramic granules without the mineral coating.
Dependencies are inferred from the claim text.