Method and apparatus for collecting signals, tracking cells, and imaging control using a photosensitive chip

An imaging control apparatus for a biological sample membrane, comprising a controller, an imaging device and a biological membrane placement mechanism, the imaging device and the biological membrane placement mechanism being communicatively connected to the controller;

• wherein the imaging device comprises a housing and a photosensitive chip,
• a darkroom space is formed inside the housing, and the photosensitive chip is placed in the darkroom space;
• the controller is configured for sending a first control signal to the biological membrane placement mechanism and controlling the biological membrane placement mechanism to attach a biological sample membrane carrying a self-luminous object to a surface of the photosensitive chip;
• the controller is further configured for sending a second control signal to the biological membrane placement mechanism and controlling the biological membrane placement mechanism to adjust a surface attachment state of the biological sample membrane until a preset placement condition is satisfied;
• the imaging control apparatus further comprising one or more cameras communicatively connected to the controller, the one or more cameras being configured for acquiring a corresponding first image when the biological sample membrane is attached to the surface of the photosensitive chip and sending the first image to the controller;
• the controller is configured for analyzing the first image to obtain a corresponding analysis result;
• the controller is further configured for generating a second control signal when the analysis result indicates that bubbles are present on a surface of the biological sample membrane;
• wherein the biological membrane placement mechanism comprises a driving member, a mechanical gripper and a roller structure, the mechanical gripper and the roller structure being electrically connected to the driving member, and the driving member being communicatively connected to the controller;
• wherein the roller structure is configured for rolling on the surface of the biological sample membrane to adjust the surface attachment state;
• wherein the driving member is configured for controlling the mechanical gripper based on the first control signal to take the biological sample membrane and to attach the biological sample membrane to the surface of the photosensitive chip;
• and
• wherein the driving member is further configured for controlling the roller structure to adjust the surface attachment state of the biological sample membrane based on the second control signal to remove the bubbles so as to satisfy the preset placement condition.