Time-dependent synthetic biological barrier material
AssigneePoly-Med, Inc.
InventorsMichael Scott Taylor, Seth Dylan McCullen, David Shalaby
Life of this patent
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Abstract
Thermally stable absorbable fiber populations, i.e. fiber populations that do not undergo thermally induced crystallization, can be intermixed to yield a stabilizing effect without altering morphological properties of a first fiber system. By addition of a stabilizing fiber population one may minimize thermally induced shrinkage and maintain physical properties of electrospun materials in the as-formed state. In one particular abstract, medical barrier materials may be formed from the electrospun materials to provide improved medical barriers for treatments.
Claims15
A thermally stable electrospun barrier comprising:
- a first population of fibers, the first population of fibers comprising at least one thermally unstable species;
- a second population of fibers, the second population of fibers comprising at least one thermally stable species;
- wherein the first population of fibers and the second population of fibers are co-mingled and distributed throughout the electrospun barrier;
- wherein the first population of fibers and the second population of fibers are distinct and independent from each other;
- wherein the fibers of each fiber population are not composite fibers comprising both the thermally unstable species and the thermally stable species;
- wherein the electrospun barrier forms at least a portion of an implantable material;
- wherein the electrospun barrier exhibits limited macroscopic changes in physical and mechanical properties when exposed to thermal or mechanical stress;
- and
- wherein the second population of fibers is present in the thermally stable electrospun barrier in an amount of from 13 to 49% by weight.
Dependencies are inferred from the claim text.