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US 12,649,908 B2Granted
Cell lines for production of adeno-associated virus
AssigneeThe University of North Carolina at Chapel Hill
InventorsHaiyan Fu, Xinghua Zeng
Life of this patent
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Abstract
This invention relates to a HEK-293 cell line that grows under animal component-free suspension conditions. This invention further relates a HEK-293 cell line that grows under adherent conditions. The cell lines may provide rapid and scalable production of adenoassociated virus (AAV) and support production of all serotypes and chimera of AAV.
Claims21
An isolated suspension HEK-293 cell deposited as ATCC No. PTA-127160.
An isolated adherent HEK-293 cell deposited as ATCC No. PTA-127161.
Dependencies are inferred from the claim text.