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US 12,649,778 B2Granted
Monoclonal antibodies and uses thereof
AssigneeNanopin Technologies, Inc.
InventorsThomas Wray Tombler, Christopher John Lyon
Life of this patent
Estimating the term…
Abstract
This invention relates generally to isolated monoclonal antibodies that binds to an epitope of the 10 kDa culture filtrate protein (CFP-10) or a peptide fragment thereof, and methods for using the same to detect Mycobacterium tuberculosis.
Claims15
An isolated monoclonal antibody, wherein said monoclonal antibody binds to an epitope of the culture filtrate antigen-10 (CFP-10) or peptide fragment thereof, wherein said monoclonal antibody comprises:
- a heavy chain with three CDRs comprising the amino acid sequences NYDGH (SEQ ID NO:
- 42), VIATIGDTYYASWAKG (SEQ ID NO:
- 43), and GDSRTSNEIFNL (SEQ ID NO:
- 44), respectively and
- a light chain with three CDRs comprising the amino acid sequences QSTRSVHNNICLS (SEQ ID NO:
- 45), SASTLAS (SEQ ID NO:
- 46), and AGCFPSKSDMYG (SEQ ID NO:
- 47), respectively.
5 more elements
Dependencies are inferred from the claim text.