Compositions comprising annexin V and HPV tumor antigen fusion polypeptides and methods for making and use
AssigneeThe Johns Hopkins University
InventorsTzyy-Choou Wu, Chien-Fu Hung, Tae Heung Kang
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Abstract
The present invention provides synthetic polypeptides comprising an annexin V protein, or a functional portion or fragment or variant thereof, conjugated to a tumor antigen, or a functional portion or fragment or variant thereof. The invention further provides methods for making said synthetic polypeptides and their use in the treatment of proliferative diseases such as cancer and tumors originating therefrom.
Claims21
A synthetic polypeptide consisting essentially of an annexin V protein, or a functional portion or fragment thereof, conjugated to an antigen, or a functional portion or fragment thereof.
A synthetic polypeptide consisting of an annexin V protein, or a functional portion or fragment thereof, conjugated to an antigen, or a functional portion or fragment thereof.
Dependencies are inferred from the claim text.