Analogs of CDDO-2P-Im and CDDO-3P-Im
AssigneeTriterpenoid Therapeutics, Inc.
InventorMichael B. Sporn
Life of this patent
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Abstract
The present disclosure relates to synthetic triterpenoids, methods for preparing such synthetic triterpenoids, and methods of using such synthetic triterpenoids to treat and/or prevent diseases or disorders such as cancers, particularly brain tumors, neuropsychiatric disorders, and neurodegenerative diseases.
Claims22
A compound or an N-oxide thereof or a pharmaceutically acceptable salt thereof, wherein the compound has a structure corresponding to Formula (I) or Formula (III):
- wherein n is an integer selected from 1 to 4 and R1 is halogen, optionally substituted carboxamide, or optionally substituted C1-6-haloalkyl.
A compound or an N-oxide thereof or a pharmaceutically acceptable salt thereof, wherein the compound has a structure corresponding to Formula (II) or Formula (IV):
- wherein n is an integer selected from 1 to 4 and R1 is halogen, optionally substituted carboxamide, or optionally substituted C1-6-haloalkyl.
Dependencies are inferred from the claim text.