Degradable magnesium-based implant devices for bone fixation
AssigneeUniversity of Pittsburgh—Of the Commonwealth System of Higher Education
InventorsPrashant N. Kumta, Abhijit Roy, Da-Tren Chou, Daeho Hong, Vijay S. Gorantla
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Abstract
The invention relates to biodegradable, magnesium alloys, compositions and composites, methods for their preparation and applications for their use as implantable medical devices in load-bearing conditions. The magnesium alloys are composed of alloying elements selected from yttrium, calcium, zirconium, zinc, and strontium, with the remainder being magnesium and impurities arising due to production, and preparation of the alloy by melting together the elements and casting the resulting melted mixture. In certain embodiments, the methods of preparation include solution treatment and hot extrusion.
Claims1
An orthopedic or craniofacial bone fixation component, comprising:
- an extruded biodegradable, magnesium alloy, consisting of:
- 1.0 weight percent of yttrium;
- 0.5 weight percent of zirconium;
- 1.0 weight percent of strontium;
- and
- a balance of magnesium and impurities due to production;
- and
- a fluoride coating applied to an outer surface of the magnesium alloy to form a magnesium fluoride layer,
- wherein the magnesium alloy with the fluoride coating exhibits no formation of hydrogen gas related swelling, and
- wherein the orthopedic or craniofacial bone fixation component is selected from the group consisting of Kirschner wire, cerclage wire, intramedullary rod, and intramedullary pin.
Dependencies are inferred from the claim text.