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US 12,648,992 B2Granted
Conditions improving poxvirus stability
AssigneeBavarian Nordic A/S
InventorsKatrine Kjaer, Markus Kalla
Life of this patent
Estimating the term…
Abstract
The present invention relates to aqueous compositions conferring improved stability to poxvirus during storage as well as to the use of such compositions and methods for preparing the same. The compositions comprise recombinant human serum albumin (rHSA), gelatin or arginine, or combinations thereof.
Claims21
An aqueous composition consisting of:
- arginine;
- Tris buffer;
- sodium chloride;
- sucrose;
- sorbitol;
- and
- a poxvirus.
4 more elements
An aqueous composition having a pH of from pH 7.0 to pH 8.5 consisting of:
- poxvirus, arginine at a concentration of from 50 mM to 150 mM, Tris buffer, sodium chloride, sucrose, and sorbitol;
- and free of a chelating agent and/or glutamic acid.
Dependencies are inferred from the claim text.