Use of Lactobacillus paracasei GM-080 for modulating immune function
AssigneeGenmont Biotech Incorporation
InventorsWan-Hua Tsai, Wen-Wei Chang, Chia-Hsuan Chou, I-Jen Wang, Wen-Ling Yeh, Jhih-Hua Jhong, Tzong-Yi Lee
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Abstract
The invention provides an extracellular vesicle and a nucleotide fragment isolated from Lactobacillus paracasei GM-080 with the deposition number BCRC 910220 and CCTCC M 204012 and use thereof. The invention also relates to a method for modulating immune function comprising administering a composition including the extracellular vesicle and the nucleotide fragment.
Claims2
A method for immunomodulation for anti-allergic or anti-inflammatory effect by stimulating the secretion of IFN-γ or IL-12, comprising administering to a subject in need thereof a therapeutically effective amount of a composition including a nucleotide which sequence is SEQ ID NO. 7, SEQ ID NO. 15, SEQ ID NO. 16, or SEQ ID NO. 18;
- wherein SEQ ID NO. 15 and SEQ ID NO. 18 stimulate the secretion of IFN-γ;
- wherein SEQ ID NO. 7 and SEQ ID NO. 16 stimulate the secretion of IL-12.
Dependencies are inferred from the claim text.