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AssigneesEmory University, Georgia Tech Research Corporation
InventorsCassandra Quave, Francois Chassagne, Lewis Marquez, Micah Dettweiler, Julia Kubanek, Anne M. Sweeney-Jones, Bhuwan Khatri Chhetri
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This disclosure relates to pentagalloyl glucose compositions and uses in managing microbial infections and compositions related thereto. In certain embodiments, this disclosure relates to compositions of pentagalloyl glucose. In certain embodiments, this disclosure relates to methods of treating or preventing a microbial infection, e.g., an antimicrobial resistant microbial infection, comprising administering to a subject in need thereof an effective amount of pentagalloyl glucose or salt thereof. In certain embodiments, the microbe is bacteria or fungi resistant to one or more antibiotic agents or antifungal agents.
A method of treating a bacterial infection comprising administering to a subject in need thereof a pharmaceutical formulation comprising an effective amount of pentagalloyl glucose or salt thereof, wherein the pharmaceutical formulation does not comprise hydrogen peroxide, and wherein the bacteria are an Acinetobacter species and are resistant to one or more antibiotic agents.
A method of treating a fungal infection comprising administering to a subject in need thereof a pharmaceutical formulation comprising an effective amount of pentagalloyl glucose or salt thereof, wherein the pharmaceutical formulation does not comprise hydrogen peroxide, and wherein the fungi are a Candida species and are resistant to one or more antibiotic agents.
Dependencies are inferred from the claim text.