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US 12,648,934 B2Granted
Combination therapy for a dopamine agonist
AssigneeAlto Neuroscience, Inc.
InventorsKathleen E. Clarence-Smith, Thomas N. Chase
Life of this patent
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Abstract
The application describes a method of reducing emesis caused by a dopamine agonist in a patient with depression who is treated with a dopamine agonist, comprising administering ondansetron in combination with the dopamine agonist.
Claims30
A method for treating a patient suffering from major depressive disorder (MDD), comprising administering to the patient a daily dose of 6 mg to 64 mg of ondansetron, or a pharmaceutically acceptable salt or solvate thereof, and a daily dose of 0.125 mg to 20 mg of pramipexole, or a pharmaceutically acceptable salt or solvate thereof.
Dependencies are inferred from the claim text.