Noninvasive measurement of left ventricular compliance
AssigneeKoninklijke Philips N.V.
InventorsOdile Bonnefous, Francois Guy Gerard Marie Vignon, Seyedali Sadeghi
Life of this patent
Estimating the term…
Abstract
A mechanism for performing a non-invasive estimate of left ventricular compliance. A temporal variation of left ventricular volume and a temporal variation of left ventricular pressure are determined by processing ultrasound data of a subject. These two temporal variations are then processed to estimate left ventricular compliance.
Claims15
A computer-implemented method for performing non-invasive estimation of left ventricular compliance for a subject, the computer-implemented method comprising:
- obtaining ultrasound data of the subject's heart, wherein the ultrasound data was captured over a time period comprising at least a portion of a cardiac cycle of the heart and comprises color M-mode ultrasound data along a direction of mitral inflow;
- determining, by processing the color M-mode ultrasound data, a velocity component along the direction of mitral inflow of the heart over the time period;
- determining a temporal variation of the left ventricular pressure from the determined velocity component by processing the velocity component using a physical model;
- determining, by processing the color M-mode ultrasound data of the obtained ultrasound data, a temporal variation of a left atrial pressure;
- modifying the determined temporal variation of the left ventricular pressure based on the determined temporal variation of the left atrial pressure;
- determining, by processing the obtained ultrasound data, a temporal variation of the left ventricle volume;
- estimating the left ventricular compliance by processing the determined temporal variation of the left ventricle volume and the modified temporal variation of the left ventricular pressure;
- and
- determining, based on the left ventricular compliance, an indicator of likelihood of diastolic heart failure.
A computer program product comprising computer program code means which, when executed on a computing device having a processing system, cause the processing system to perform a method comprising:
- obtaining ultrasound data of a subject's heart, wherein the ultrasound data was captured over a time period comprising at least a portion of a cardiac cycle of the heart and comprises color M-mode ultrasound data along a direction of mitral inflow;
- determining, by processing the color M-mode ultrasound data, a velocity component along the direction of mitral inflow of the heart over the time period;
- determining a temporal variation of the left ventricular pressure from the determined velocity component by processing the velocity component using a physical model;
- determining, by processing the color M-mode ultrasound data of the obtained ultrasound data, a temporal variation of a left atrial pressure;
- modifying the determined temporal variation of the left ventricular pressure based on the determined temporal variation of the left atrial pressure;
- determining, by processing the obtained ultrasound data, a temporal variation of the left ventricle volume;
- estimating the left ventricular compliance by processing the determined temporal variation of the left ventricle volume and the modified temporal variation of the left ventricular pressure;
- and
- determining, based on the left ventricular compliance, an indicator of likelihood of diastolic heart failure.
A processing arrangement for performing estimation of left ventricular compliance for a subject, the processing arrangement being configured to:
- obtain ultrasound data of the subject's heart, wherein the ultrasound data was captured over a time period comprising at least a portion of a cardiac cycle of the heart and comprises color M-mode ultrasound data along a direction of mitral inflow;
- determine, by processing the color M-mode ultrasound data, a velocity component along the direction of mitral inflow of the heart over the time period;
- determine a temporal variation of the left ventricular pressure from the determined velocity component by processing the velocity component using a physical model;
- determine, by processing the color M-mode ultrasound data of the obtained ultrasound data, a temporal variation of a left atrial pressure;
- modify the determined temporal variation of the left ventricular pressure based on the determined temporal variation of the left atrial pressure;
- determine, by processing the obtained ultrasound data, a temporal variation of the left ventricle volume;
- estimate the left ventricular compliance by processing the determined temporal variation of the left ventricle volume and the modified temporal variation of the left ventricular pressure;
- and
- determine, based on the left ventricular compliance, an indicator of likelihood of diastolic heart failure.
Dependencies are inferred from the claim text.