Proteolytically stable U1-agatoxin-Ta1b variant polypeptides for pest control
AssigneeVestaron Corporation
InventorsKyle Schneider, Alexandra Haase, Breck Davis, Ryan Garrett
Life of this patent
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Abstract
New insecticidal proteins, nucleotides, peptides, and their expression in plants. Methods of producing new nucleotides and new peptides, new processes, new production techniques, new formulations, and new organisms. The present disclosure is also related to and describes novel peptides called TVPs, which are non-natural peptide variations based upon the U1-agatoxin-Ta1b toxin derived from the Hobo spider. Here, we describe: genes encoding TVPs; formulations and combinations comprising TVP genes and/or peptides; and methods using the same that are useful for the control of pests.
Claims10
A pesticidal U1-agatoxin-Ta1b variant polypeptide (TVP) comprising the amino acid sequence set forth in any one of SEQ ID NO:
- 2, 49, or 51;
- or an agriculturally acceptable salt thereof.
A pesticidal U1-agatoxin-Ta1b variant polypeptide (TVP) consisting of the amino acid sequence set forth in any one of SEQ ID NO:
- 2, 49, or 51;
- or an agriculturally acceptable salt thereof.
A pesticidal U1-agatoxin-Ta1b variant polypeptide (TVP) comprising the amino acid sequence set forth in SEQ ID NO:
- 51, or an agriculturally acceptable salt thereof.
A pesticidal U1-agatoxin-Ta1b variant polypeptide (TVP) consisting of the amino acid sequence set forth in SEQ ID NO:
- 51, or an agriculturally acceptable salt thereof.
A pesticidal U1-agatoxin-Ta1b variant polypeptide (TVP) comprising the amino acid sequence set forth in SEQ ID NO:
- 2, or an agriculturally acceptable salt thereof.
A pesticidal U1-agatoxin-Ta1b variant polypeptide (TVP) consisting of the amino acid sequence set forth in SEQ ID NO:
- 2, or an agriculturally acceptable salt thereof.
A pesticidal U1-agatoxin-Ta1b variant polypeptide (TVP) comprising the amino acid sequence set forth in SEQ ID NO:
- 49, or an agriculturally acceptable salt thereof.
A pesticidal U1-agatoxin-Ta1b variant polypeptide (TVP) consisting of the amino acid sequence set forth in SEQ ID NO:
- 49, or an agriculturally acceptable salt thereof.
A composition comprising a pesticidal U1-agatoxin-Ta1b variant polypeptide (TVP) and at least one excipient;
- wherein the TVP comprises the amino acid sequence set forth in any one of SEQ ID NO:
- 2, 49, or 51, or an agriculturally acceptable salt thereof.
A kit comprising:
- (1) a pesticidal U1-agatoxin-Ta1b variant polypeptide (TVP) comprising the amino acid sequence set forth in any one of SEQ ID NO:
- 2, 49, or 51, or an agriculturally acceptable salt thereof;
- and (2) at least one excipient.
Dependencies are inferred from the claim text.