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US 12,648,571 B2Granted
Compositions including antimicrobial polymer-peptide conjugates and uses thereof
AssigneeUniversity of Puerto Rico
InventorsEduardo Nicolau, Valerie Ortiz Gómez
Life of this patent
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Abstract
Disclosed herein are PEG-maximin H5 peptide conjugates and methods for using the same in the treatment or prevention of biofilms and biofouling.
Claims20
A peptide conjugate comprising a polyethylene glycol (PEG) polymer conjugated to an antimicrobial peptide (AMP) comprising the amino acid sequence ILGPVLGLVSDTLDDVLGILC-COOH (SEQ ID NO:
- 2), or a PEG polymer conjugated to an AMP having an amino acid sequence of SEQ ID NO:
- 2, wherein the AMP is conjugated to the PEG polymer via a thiol bond, optionally wherein the PEG polymer is conjugated to the N-terminus or the C-terminus of the AMP.
Dependencies are inferred from the claim text.