Mass spectrometry method and mass spectrometer

A mass spectrometry method comprising steps of:

• generating product ions by collision-induced dissociation and radical attachment dissociation of a precursor ion derived from a sample molecule;
• and
• obtaining product ion spectrum data by mass-separating and detecting the product ions, wherein:
• product ions are further generated by only one of the collision-induced dissociation and the radical attachment dissociation,
• the mass spectrometry method further comprising steps of:
• comparing intensity of a mass peak included in the product ion spectrum data generated based on a detection result of the product ions generated by only one dissociation operation with intensity of a mass peak included in the product ion spectrum data generated based on a detection result of the product ions generated by the collision-induced dissociation and the radical attachment dissociation.

A mass spectrometer comprising:

• a reaction chamber into which a precursor ion derived from a sample molecule is introduced;
• a collision gas supply part configured to supply collision gas to the reaction chamber;
• a radical supply part configured to supply hydrogen radicals, oxygen radicals, nitrogen radicals, or hydroxyl radicals to the reaction chamber;
• a dissociation operation control part configured to control operations of the collision gas supply part and the radical supply part to generate product ions by collision-induced dissociation and radical attachment dissociation of the precursor ion inside the reaction chamber;
• an ion detection part configured to mass-separate and detect ions ejected from the reaction chamber;
• and
• a spectrum data generation part configured to generate spectrum data based on a detection result by the ion detection part, wherein:
• the dissociation operation control part is configured to further dissociate the precursor ion by only one of the collision-induced dissociation and the radical attachment dissociation inside the reaction chamber to generate the product ions,
• the mass spectrometer further comprising:
• a mass peak intensity comparison part configured to compare intensity of a mass peak included in the product ion spectrum data generated based on a detection result of the product ions generated by only one dissociation operation with intensity of a mass peak included in the product ion spectrum data generated based on a detection result of the product ions generated by the collision-induced dissociation and the radical attachment dissociation.