Tissue sampling kit

A sampling device configured for mounting in a reaction chamber providing a reaction volume defined between a base of the reaction chamber and the sampling device when the tissue sampling device is mounted in the reaction chamber, the sampling device comprising:

• a proximal handling portion and;
• a distal scraping portion comprising a scraping formation configured to collect a sample of tissue onto the scraping formation when the distal scraping formation is rubbed against a surface of the tissue, said scraping formation comprising scraping edges configured to collect tissue fibers
• an internal lumen extending from a top to at least one distal aperture in a sidewall of the distal scraping portion, said lumen being configured to supply reaction liquid from a distal end of the tissue sampling device to the reaction volume via the at least one distal aperture disposed in the sidewall of the distal scraping portion when the tissue sampling device is mounted in the reaction chamber.