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US 12,644,094 B2Granted
Serpin production
AssigneeSociete des Produits Nestle S.A.
InventorsStephane Duboux, Mireille Golliard, Michiel Kleerebezem
Life of this patent
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Abstract
Use of a fructose disaccharide or fructooligosaccharide, for increasing protein production in Bifidobacterium longum subsp longum.
Claims12
A method for increasing serpin protein levels in Bifidobacterium longum subsp longum, wherein the method comprises growing the Bifidobacterium longum subsp longum in a culture medium having a concentration of residual glucose at an end of fermentation that is less than 0.4 wt %, and wherein the culture medium comprises 0.5 to 1.5 wt % of (i) fructose disaccharide or (ii) a combination of fructose disaccharide and fructooligosaccharide (FOS).
Dependencies are inferred from the claim text.