Back to results
US 12,644,089 B2Granted
Biological fluidic system
AssigneeThe Interdisciplinary Center Herzliya Projects Ltd.
InventorsGilad Binyamin Gome, Iddo Yehoshua Wald, Andrey Grishko
Life of this patent
Estimating the term…
Abstract
Provided is a biological fluidic system that provides a high degree of sterilization by performing the biological processing in a closed system in which the fluid is contained in chambers that are isolated from the environment in a manner that does not permit ingress of contaminants.
Claims16
A system for cultivating microorganisms or performing biological processing, comprising:
- a processing arrangement comprising:
- two pliable polymeric sheets oppositely disposed from each other forming first and second sides of the processing arrangement, the pliable polymeric sheets are fixed to one another at one or more portions of the respective sheets, and comprising:
- a processing chamber comprising:
- oppositely disposed ports;
- a cultivation chamber in communication with one of the ports;
- and
- a duct extending between the ports, along a pathway including a flow driving-region, to permit fluid flow between the two ports through the duct, and
- a base comprising:
- a fluid driving mechanism configured for operatively coupling with said processing arrangement, the fluid driving mechanism comprising:
- one or more magnetic engagement elements;
- and
- a driving motor magnetically coupled to said one or more magnetic engagement elements along the pathway including the flow-driving region on the second side of the processing arrangement, the driving motor configured to move the one or more magnetic engagement elements along a rotational pathway, the rotational pathway for alignment with the pathway including the flow driving-region of the duct;
- wherein, when the processing arrangement is operatively coupled to the base and the first side of the processing arrangement faces the base, each of the one or more magnetic engagement elements is positioned on the second side of the processing arrangement at one of a plurality of positions along the pathway including the flow-driving region to form a magnetic engagement with the driving motor, so that when the driving motor moves the one or more magnetic engagement elements along at least a portion of the pathway including the flow-driving region, each of said one or more magnetic engagement elements in the magnetic coupling applies pressure to the pathway including the flow-driving region, resulting in propelling the fluid in the pathway including the flow-driving region, and
- wherein, when said processing arrangement is not operatively coupled to the base, said one or more magnetic elements are adapted to be magnetically and removably attached to a surface of the base.
11 more elements
A biological fluidic system comprising:
- a biological arrangement comprising:
- two pliable polymeric sheets, that are oppositely disposed from each other to form first and second sides of the biological arrangement, the pliable polymeric sheets being fixed together at corresponding portions to one another:
- a plurality of processing chambers;
- oppositely disposed ports, at least one of the ports in communication with at least one of the plurality of processing chambers;
- and
- a duct extending between the ports, along a pathway including a flow-driving region, to permit fluid flow between the two ports through the duct, and
- a base structure comprising:
- a fluid driving mechanism configured for operatively coupling with said biological arrangement, the fluid driving mechanism comprising:
- one or more magnetic engagement elements;
- and
- a driving motor magnetically coupled to said to one or more magnetic engagement elements on the second side of the biological arrangement, the driving motor configured to the one or more magnetic engagement elements along a rotational pathway, the rotational pathway for alignment with the pathway including the flow-driving region of the duct;
- wherein, when the biological arrangement is operatively coupled to the base structure and the first side of the biological arrangement faces the base structure, each of the one or more magnetic engagement elements positioned on the second side of the biological arrangement at one of a plurality of positions along the pathway including the flow-driving region to form a magnetic engagement with the driving motor, so that when the driving motor moves the one or more magnetic engagement elements along the pathway including the flow-driving region, said one or more magnetic engagement elements in the magnetic applies pressure to the pathway including the flow-driving region, resulting in propelling the fluid in the pathway including the flow-driving region, and
- wherein, when said processing arrangement is not operatively coupled to the base, said one or more magnetic elements are adapted to be magnetically and removably attached to a surface of the base.
10 more elements
Dependencies are inferred from the claim text.