Neural lattice device for characterization of neuron behavior
AssigneeInternational Business Machines Corporation
InventorsSagarika Mukesh, Steven Holmes, John S. Werner, Benjamin Hardy Wunsch, Arkadiy O. Tsfasman
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Abstract
A neural lattice device includes a substrate having formed therein one or more wells and one or more supply ducts. A channel network includes one or more channels configured to establish fluid communication among the at least one well and the at least one supply duct. A reservoir is coupled to the substrate and configured to hold a fluid, and a cover is disposed against an upper surface of the substrate and configured to hermetically seal the wells, the supply ducts and the channel network.
Claims9
A method of fabricating a neural lattice device, the method comprising:
- forming at least one well in a substrate, the well configured to hold a biological neuron;
- forming at least one supply duct in the substrate, the supply duct configured to receive a nutrient fluid,
- forming in the substrate a channel network including one or more channels configured to establish fluid communication among the at least one well and the at least one supply duct;
- coupling a reservoir to the substrate, the reservoir configured to hold a fluid;
- and
- disposing a cover against an upper surface of the substrate and configured to hermetically seal the at least one well, the at least one supply duct, and the channel network,
- wherein forming the at least one growth barrier includes forming a plurality of growth barriers surrounding the at least one supply duct.
Dependencies are inferred from the claim text.