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US 12,643,098 B2Granted
Ferromagnetic rotors for agitating the liquid in a microwell
AssigneeAccess Medical Systems, Ltd.
InventorsHong Tan, Haode Chen, Genqian Li
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Abstract
Introduced here are rotors that can be placed inside of microplate wells that include liquid samples. Each rotor can be comprised of a ferromagnetic material. Accordingly, when a rotor is subjected to an external rotational magnetic field, the rotor spins and agitates the liquid sample inside the corresponding well. The spin speed may be adjusted by changing the rotation speed, direction, and/or orientation of the external rotational magnetic field. The rotor typically includes a central cavity within which a probe can be suspended during the biochemical test.
Claims17
A system comprising:
- a plate that includes one or more wells, each of which has a diameter of no more than 20 millimeters (mm) and a depth of no more than 20 mm;
- a rotor that has a substantially cylindrical structural body with an open top end, an outer wall, and an inner wall disposed circumferentially around a central cavity,
- wherein the substantially cylindrical structural body is comprised of a ferromagnetic material, such that when the rotor is placed in a given well of the one or more wells and subjected to a rotating magnetic field, the rotor causes agitation throughout a liquid column formed by a sample in the given well;
- and
- a probe that is coated with analyte-binding molecules along one end that interact with analyte molecules in the sample during a biochemical test,
- wherein the open top end enables the probe to be suspended into the central cavity of the rotor during the biochemical test.
3 more elements
Dependencies are inferred from the claim text.