Medical fluid generation system

A tubing set for use with a machine that generates a medical fluid, the tubing set comprising:

• a line for connecting to the machine or to a fluid carrying structure extending from the machine;
• a Y or T-connector in fluid communication with the line;
• a first manifold line in fluid communication with the Y or T-connector;
• a second manifold line in fluid communication with the Y or T-connector;
• a plurality of multi-chamber medical fluid containers each including a first chamber and a second chamber;
• a plurality of first filling lines in fluid communication with the first manifold line and the first chambers of the plurality of multi-chamber medical fluid containers;
• a plurality of second filling lines in fluid communication with the second manifold line and the second chambers of the plurality of multi-chamber medical fluid containers;
• and
• at least one sterilizing filter located (i) upstream of the Y or T-connector or (ii) in each of the first and second manifold lines.