Back to results
US 12,642,875 B2Granted
Liposomal nanocarrier delivery system for targeting active CD44 molecule, preparation method therefor, and uses thereof
AssigneeBeijing Inno Medicine Co., Ltd.
InventorsQian Ma, Jiefang Sun
Life of this patent
Estimating the term…
Abstract
A liposomal nanocarrier delivery system for targeting an active CD44 molecule, preparation method therefor, and uses thereof. The surface of the liposome is partially modified by a targeting ligand, wherein the targeting ligand is a ligand that can be specifically combined with the active CD44 molecule. The liposomal nanocarrier delivery system can be used for diagnosing, preventing, and treating vulnerable plaque or diseases related to vulnerable plaque.
Claims19
A liposome nanocarrier delivery system, characterized in that the surface of the nanocarrier is partially modified by a targeting ligand;
- wherein the targeting ligand is a hyaluronic acid, a pharmaceutically acceptable salt of the hyaluronic acid, or a C1 to C6 alkyl ester of the hyaluronic acid;
- wherein the hyaluronic acid, pharmaceutically acceptable salt of the hyaluronic acid, or C1 to C6 alkyl ester of the hyaluronic acid has a molecular weight in the range of 1-20 KDa;
- wherein the nanocarrier further comprises a long-chain phospholipid and cholesterol;
- and
- wherein the nanocarrier is loaded with rosuvastatin, or a pharmaceutically acceptable salt thereof.
2 more elements
Dependencies are inferred from the claim text.