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US 12,642,760 B2Granted
Implantable capsule
AssigneesRelease Therapeutics SA, Les Hopitaux Universitaires De Geneve, Universite De Geneve Geneve
InventorsAurélien Lathuilière, Julien Grogg, Nicolas Mach
Life of this patent
Estimating the term…
Abstract
Implantable capsule comprising a cell receiving portion (2) comprising a porous membrane (5) surrounding a cell receiving chamber (13) for receiving immortalized cells in a liquid media therein for the secretion of therapeutic agents. The capsule further comprises a cell support matrix (7) inserted within the cell receiving chamber (13) configured for the arrangement of the immortalized cells within the cell receiving chamber.
Claims17
An implantable capsule comprising a cell receiving portion comprising:
- (a) a porous membrane surrounding a cell receiving chamber for receiving genetically engineered immortalized cells in a liquid media therein for the secretion of therapeutic agents, and
- (b) a membrane support mounted in the cell receiving chamber configured for providing structural support to the porous membrane, the membrane support comprising a coil made of a biocompatible material,
- wherein the capsule further comprises a cell support matrix comprising at least one yarn inserted within the cell receiving chamber configured for the arrangement of the immortalized cells within the cell receiving chamber, said coil surrounding said at least one yarn.
Dependencies are inferred from the claim text.