Ophthalmic lenses and their manufacture by in-mold modification

A method for forming an ophthalmic lens, the method comprising:

• (a) providing a mold assembly comprised of a base curve and a front curve, the base curve and the front curve defining and enclosing a cavity therebetween, the cavity containing a reactive monomer mixture, wherein the reactive monomer mixture comprises a monomer suitable for making the ophthalmic lens, a first polymerization initiator that is capable of being activated at a first wavelength, a first functional moiety chemically linked to the first polymerization initiator, and a second polymerization initiator that is capable of being activated by a second activation that does not substantially activate the first polymerization initiator, wherein at least one of the base curve or front curve is light transmissive;
• (b) exposing one or more selective regions of the reactive monomer mixture to a source of actinic radiation at the first wavelength to thereby selectively polymerize a portion of the reactive monomer mixture, wherein the source of actinic radiation includes a plurality of selectively controllable beams of actinic radiation and the exposure is conducted according to a predetermined script to cause selective polymerization of the reactive monomer mixture in a predetermined pattern within the cavity of the mold assembly, and wherein the selectively polymerized portion incorporates the first functional moiety;
• (c) exposing the reactive monomer mixture to the second activation to activate the second polymerization initiator and cure the reactive monomer mixture;
• (d) removing the ophthalmic lens from the mold assembly;
• and
• (e) extracting unreacted first polymerization initiator from the ophthalmic lens.