Device and method to evaluate a fluid sample on a single-use multianalyte consumable
AssigneeSiemens Healthcare Diagnostics Inc.
InventorJennifer Samproni
Life of this patent
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Abstract
Single-use diagnostic consumables for use in performing multiple analyses on a fluid sample are provided. The diagnostic consumables include a first sensing region configured for analysis of at least one analyte in a fluid sample that has been received by the diagnostic consumable. The diagnostic consumable further includes a fluid transport material configured to flow a portion of the fluid sample into a second sensing region fluidically connected to the fluid transport material and configured for performing a second analysis of the fluid sample. Methods for performing multiple analyses of a fluid sample on a single-use diagnostic consumable are also provided.
Claims25
A single-use diagnostic consumable for use in the analysis of a fluid sample, the diagnostic consumable comprising:
- a substrate having a top surface, a bottom surface, and a thickness therebetween, the substrate including:
- a first sensing region that includes at least one sensor configured for a first analysis of a fluid sample that has been received by the diagnostic consumable;
- a second sensing region configured for a second analysis of the fluid sample;
- a fluid transport material configured to flow a portion of the fluid sample into the second sensing region;
- and
- a sample input port for receiving the fluid sample, the sample input port fluidically connected to the fluid transport material;
- wherein:
- the first sensing region or the second sensing region extends through the thickness of the substrate and is open at the top surface and the bottom surface of the substrate;
- and
- the fluid transport material or the second sensing region comprises a reagent that reacts with an analyte of interest in the fluid sample.
A single-use diagnostic consumable for use in the analysis of a fluid sample, the diagnostic consumable comprising:
- a first sensing region that includes at least one sensor configured for a first analysis of a fluid sample that has been received by the diagnostic consumable;
- a second sensing region configured for a second analysis of the fluid sample;
- a fluid transport material configured to flow a portion of the fluid sample into the second sensing region;
- and
- a sample input port for receiving the fluid sample, the sample input port fluidically connected to the fluid transport material;
- wherein:
- the fluid transport material substantially surrounds the sample input port;
- and
- the fluid transport material comprises a plasma separation membrane configured to separate plasma and blood cells in a whole blood sample to produce a plasma sample for analysis in the second sensing region.
Dependencies are inferred from the claim text.