Bioabsorbable magnesium alloy for implants with engineered absorption
AssigneeMagsorbeo Biomedical Corp.
InventorsJacob Drew Edick, Carolyn Joan Lahti Woldring
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Abstract
The present disclosure generally relates to a magnesium alloy including about 2-7% by weight zinc; about 0.2-3% by weight calcium; about 0-1.0% by weight of an alloying element; and a balance of magnesium. The magnesium alloy may include a ternary absorption profile including a first absorption rate, second absorption rate, and third absorption rate, the second absorption rate being approximately slower than the first absorption rate and the third absorption rate. The magnesium alloy may be formed as a portion or more of a bodily implant.
Claims11
A magnesium alloy comprising:
- zinc in an amount within a range from greater than 2 wt. % to about 4 wt. %;
- calcium in an amount within a range from about 1 wt. % to about 2 wt. %, wherein a ratio of zinc to calcium is between 2.5:1 and 3.0:1;
- manganese in an amount within a range from about 0.7 wt. % to about 1.0 wt. %;
- and a balance of magnesium,
- wherein a microstructure of the magnesium alloy comprises an a-Mg phase matrix and nanometric intermetallic particles,
- wherein the nanometric intermetallic particles comprise:
- a binary phase Mg2Ca;
- and
- a ternary phase of Ca2Mg6Zn3 dispersed in the α-Mg phase matrix, and
- wherein the microstructure provides an absorption rate of the alloy of less than 0.2 millimeters per year for a duration not less than 500 hours.
A magnesium alloy comprising:
- zinc in an amount within a range from about 1.4 wt. % to about 7.0 wt. %;
- calcium in an amount within a range from about 0.5 wt. % to about 3 wt. %, wherein a ratio of zinc to calcium is between 2.5:1 and 3.0:1;
- manganese in an amount within a range from about 0.7 wt. % to about 1.0 wt. %;
- and
- a balance of magnesium,
- wherein a microstructure of the magnesium alloy comprises nanometric intermetallic particles including Mg2Ca and Ca2Mg6Zn3 dispersed in an α-Mg phase matrix, and
- wherein the microstructure provides an absorption rate of the alloy of less than 0.1 millimeters per year for a duration not less than 500 hours.
A product comprising:
- a magnesium alloy comprising:
- zinc in an amount within a range from about 1.4 wt. % to about 7.0 wt. %;
- calcium, wherein a ratio of zinc to calcium is between 2.5:1 and 3.0:1;
- manganese in an amount within a range from about 0.7 wt. % to about 1.0 wt. %;
- and
- a balance of magnesium,
- wherein a microstructure of the magnesium alloy comprises nanometric intermetallic particles including Mg2Ca and Ca2Mg6Zn3 dispersed in an α-Mg phase matrix, and
- wherein the microstructure provides an absorption rate of the alloy of less than 0.1 millimeters per year for a duration not less than 500 hours.
Dependencies are inferred from the claim text.