Compositions and methods for regulating fatty acids

Abstract

Among the various aspects of the present disclosure relates to methods and compositions useful in convert inflammatory dietary fatty acids (omega 6) to anti-inflammatory fatty acids (omega 3). Specifically, the present disclosure provides methods and compositions for increasing n-3 desaturase expression or activity in a subject. The disclosure provides various compositions for providing increased n-3 desaturase expression or activity including a variety of viral vector and engineered microorganisms. The disclosure provides, in part, methods for reducing local and/or systemic inflammation, improving wound healing, preventing premature cellular senescence, treating or preventing a disease, disorder, or condition related to inflammation or obesity and treating or preventing arthritis.

Dependencies are inferred from the claim text.