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US 12,637,664 B2Granted
Purification matrices comprising AAV-binding polypeptides and methods of using the same
AssigneesDonaldson Company, Inc., Duke University
InventorsKelli M. Luginbuhl, Michael Dzuricky, Zachary Elmore, Aravind Asokan
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Abstract
The application provides fusion proteins comprising an adeno-associated virus (AAV)-binding polypeptide and a polypeptide having phase behavior. Furthermore, the application provides purification matrices comprising these AAV-binding polypeptides, and methods of using the same for purifying AAV particles.
Claims11
A fusion protein comprising an AAV-binding polypeptide and a polypeptide having phase behavior, wherein the AAV-binding polypeptide comprises the amino acid sequence of SEQ ID NO:
- 52.
Dependencies are inferred from the claim text.