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AssigneePTC Therapeutics MP, Inc.
InventorsDaniel E. Levy, Neil Smith, Jonathan Reis, Hiroshi Yoshino, Taichi Komoda, Yuichi Shiro, Shunichi Murata, Takayoshi Matsumoto, Kaito Kishimoto
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The present invention relates to new pharmaceutical salts and/or co-crystals of sepiapterin which exhibit improved properties. In particular, the invention relates to salts of sepiapterin with improved stability. The invention also relates to pharmaceutical compositions including a pharmaceutically effective amount of one or more salts and/or co-crystals of sepiapterin, as well as methods of treating tetrahydrobiopterin-related disorders including administration of a sepiapterin salt and/or co-crystal of the invention to a subject in need thereof.
A pharmaceutically acceptable salt of sepiapterin, wherein the pharmaceutically acceptable salt is a nicotinate salt, a 1:1 tartrate salt, or a 2:1 tartrate salt.
Dependencies are inferred from the claim text.