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US 12,636,621 B2Granted
Filtration membrane
AssigneeThe Regents of the University of California
InventorsBenjamin W. Chui, Shuvo Roy, Nathan Wright
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Abstract
The present disclosure provides an improved filtration membrane suitable for filtration of blood in vivo. The improved filtration membrane is resistant to breakage with minimal areal penalty due to presence of a system of supports on the backside of the membrane. The minimal areal penalty is achieved by using supports that provide a hierarchical scaffolding that comprises ribs of two different heights as disclosed herein.
Claims16
A filtration membrane suitable for filtering blood in vivo, the filtration membrane comprising:
- a membrane section comprising:
- a plurality of nanopores and comprising a planar first surface;
- a ribbed second surface, wherein the first surface is opposite the ribbed second surface, the ribbed second surface comprising ribs of a first height and ribs of a second height which is higher than the first height;
- the ribs of the first height defining a plurality of first windows arranged in a grid pattern, the first windows comprising the plurality of nanopores;
- the ribs of the second height defining a plurality of second windows arranged in a grid pattern, each of the plurality of second windows comprising the plurality of first windows;
- and
- a support section forming a third window comprising the plurality of second windows, wherein the support section is attached to the ribbed second surface of the membrane section at a periphery of the membrane section and has a third height higher than the ribs of the second height,
- wherein the surface area of the ribbed second surface of the membrane enclosed by the third window is in the range of 0.1 mm2-10 mm2.
5 more elements
Dependencies are inferred from the claim text.